CYTOPLASMIC GRANULE FORMATION IN MYELOCYTES
نویسندگان
چکیده
منابع مشابه
Cytoplasmic Granule Formation in Myelocytes
The intracellular flow of tritiated lysine as revealed by electron microscope radioautography was studied in heterophilic myelocytes of rabbit marrow. Label over the Golgi complex rose to a maximum of 37% of total cytoplasmic grains 30 min after initial exposure to the tracer and fell to 11% after 3 to 4 hr of incubation. Coincident with decrease in label over the Golgi complex, grain counts ov...
متن کاملFormation of cytoplasmic granules in human eosinophilic myelocytes: an electron microscope autoradiographic study.
T HE CYTOPLASMIC GRANULES of eosinophils may be considered a form of lysosome, for they are membrane bounded structures containing, among other substances, hydrolytic enzymes.’ These granules appear in the immature cell as large membrane bounded structures with a homogeneous electron dense content; as the cell matures, a crystalloid inclusion commonly develops within the granule.2.3 Electron mi...
متن کاملDifferentiated cytoplasmic granule formation in quiescent and non-quiescent cells upon chronological aging
Stationary phase cultures represent a complicated cell population comprising at least two different cell types, quiescent (Q) and non-quiescent (NQ) cells. Q and NQ cells have different lifespans and cell physiologies. However, less is known about the organization of cytosolic protein structures in these two cell types. In this study, we examined Q and NQ cells for the formation of several stat...
متن کاملA novel type of cytoplasmic granule in bovine neutrophils
We obtained cell preparations containing greater than 95% neutrophils from freshly drawn bovine blood. The cells were suspended in sucrose and disrupted in a Dounce homogenizer, and the postnuclear supernate was fractionated by zonal differential sedimentation and by isopycnic equilibration. The subcellular fractions were characterized biochemically by testing for marker enzymes and other const...
متن کاملALS-Associated TDP-43 Induces Endoplasmic Reticulum Stress, Which Drives Cytoplasmic TDP-43 Accumulation and Stress Granule Formation
In amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration, TAR DNA binding protein 43 (TDP-43) accumulates in the cytoplasm of affected neurons and glia, where it associates with stress granules (SGs) and forms large inclusions. SGs form in response to cellular stress, including endoplasmic reticulum (ER) stress, which is induced in both familial and sporadic forms of ALS. He...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 1966
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.29.2.307